PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Saponins and aromatic compounds from seeds inhibit NO production and IL-1β secretion in cell models [PMID:39102757, 37778669]
White hyacinth bean polysaccharides reduced blood glucose levels and improved intestinal impairment in T2DM rats [PMID:37813213, 39393741]
Extracts and chikusetsusaponin IVa inhibited body weight and fat mass increase in high-fat diet mice and inhibited adipocyte differentiation [PMID:30177649, 28106337]
Dry-fried seeds showed enhanced anti-UC efficacy in DSS-induced murine models compared to raw seeds [PMID:41270913]
Extracts significantly rescued SRMD in rats by decreasing inflammatory mediators such as IL-18, IL-1β, and TNF-α [PMID:32801474]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 32530295 (2021) — Dolichos Lablab-an underutilized crop with future potentials for food and nutrition security: a review. · Critical reviews in food science and nutrition
- 2.PMID: 39102757 (2024) — Saponins from Dolichos lablab seeds with anti-inflammatory activity. · Bioorganic chemistry
- 3.PMID: 38961686 (2025) — An underutilized bean: hyacinth bean [Lablab purpureus (L.) sweet]: bioactive compounds, functional activity, and future food prospect and applications. · Journal of the science of food and agriculture
- 4.PMID: 22435478 (2009) — Morphological and reproductive characterization in hyacinth bean, Lablab purpureus (L.) sweet germplasm with clinically proven nutraceutical and pharmaceutical traits for use as a medicinal food. · Journal of dietary supplements
- 5.PMID: 38274205