PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Decoctions and total alkaloid fractions of S. sessilifolia showed significant dose-dependent antitussive effects in animal models [PMID:20222432, PMID:19031364].
Protostemonine significantly attenuated LPS-induced inflammatory cell infiltration and reduced pro-inflammatory cytokines in mice [PMID:29047459].
S. sessilifolia extract significantly reduced serum markers and provided renal protection in mouse models [PMID:41317808].
A shampoo containing 0.12% Stemona root crude extract resulted in a 24.44% cure rate in schoolgirls, which was lower than 4% dimeticone [PMID:41258179, PMID:37352268].
Non-alkaloids extract reversed resistance to adriamycin, paclitaxel, and vincristine in MCF-7/ADR cells by modulating P-glycoprotein [PMID:26190165].
Evidence summary
PubMed sources
- 1.PMID: 38104498 (2024) — Characteristic alkaloids from Stemona sessilifolia with lung protective effects. · Bioorganic chemistry
- 2.PMID: 17566919 (2007) — Stilbenoids from Stemona sessilifolia. · Journal of Asian natural products research
- 3.PMID: 41317808 (2026) — Renoprotective effects of Stemona sessilifolia via suppression of the c-Myc/c-Fos/MAPK pathway in hyperuricemic nephropathy. · Journal of ethnopharmacology
- 4.PMID: 17701569 (2007) — Antibacterial constituents from Stemona sessilifolia. · Journal of Asian natural products research
- 5.PMID: 26190165 (2016) — Non-alkaloids extract from Stemona sessilifolia enhances the activity of chemotherapeutic agents through P-glycoprotein-mediated multidrug-resistant cancer cells.