PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 9 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Seed extracts rescued depressive behavior in chronic, unpredicted, mild stress (CUMS)-induced rats [PMID:35489661].
Seed powder improved cognitive function and α7nAChR protein expression in AD model rats [PMID:23443809]; seed extract inhibited Aβ-peptide aggregation and reduced cognitive deficits in 5xFAD mice [PMID:32922281].
Dietary seed oil suppressed anti-erythrocyte autoantibodies and prolonged survival [PMID:8200132].
Seed oil decreased plasma total cholesterol, HDL cholesterol, triglycerides, and phospholipids [PMID:1453880].
Evidence summary
PubMed sources
- 1.PMID: 35489661 (2022) — Platycladus orientalis seed extract as a potential triple reuptake MAO inhibitor rescue depression phenotype through restoring monoamine neurotransmitters. · Journal of ethnopharmacology
- 2.PMID: 23443809 (2013) — Effect of arborvitae seed on cognitive function and α7nAChR protein expression of hippocampus in model rats with Alzheimer's disease. · Cell biochemistry and biophysics
- 3.PMID: 32922281 (2020) — Modulation of the Aβ-Peptide-Aggregation Pathway by Active Compounds From Platycladus orientalis Seed Extract in Alzheimer's Disease Models. · Frontiers in aging neuroscience
- 4.PMID: 8200132 (1994) — Dietary Platycladus orientalis seed oil suppresses anti-erythrocyte autoantibodies and prolongs survival of NZB mice. · Clinical immunology and immunopathology
- 5.PMID: 31542470