PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Methanol extract of the bark exhibited an antibiotic potentiating effect, reducing the MIC of clindamycin by 16-fold and showing synergistic activity with penicillin [PMID:38694794]
Methanol and chloroform extracts significantly reduced the time for epithelization and wound contraction in excision and burn models, and increased breaking strength in incision and dead space models [PMID:20582204]
Hydroalcoholic extract from the stem bark demonstrated significant anti-arthritic and anti-inflammatory activity [PMID:31031464]
Ethanol extracts of leaves and unripe pods significantly protected rat kidneys from gentamicin-induced histopathological changes [PMID:20502576]
Oral pretreatment significantly decreased serum toxicity markers, elevated antioxidant enzyme activities, and reduced tumor incidences [PMID:24082504]
Safety & adverse effects
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 38694794 (2024) — Antibiotic potentiating effect of Bauhinia purpurea L. against multidrug resistant Staphylococcus aureus. · Frontiers in microbiology
- 2.PMID: 34167392 (2022) — Study of cardioprotective activity of the methanolic extract of the aerial parts of Bauhinia madagascariensis compared to Bauhinia purpurea against adrenaline-induced myocardial toxicity in rats. · Drug and chemical toxicology
- 3.PMID: 3051929 (1988) — The separation of immunocyte subpopulations by use of various lectins. · Advances in experimental medicine and biology
- 4.PMID: 35268634 (2022) — Hepatoprotective Potential of Malaysian Medicinal Plants: A Review on Phytochemicals, Oxidative Stress, and Antioxidant Mechanisms. · Molecules (Basel, Switzerland)
- 5.PMID: 9343930