PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Alcoholic stem bark extract (100-200 mg/kg) exhibited significant hepatoprotective activity in CCl4-intoxicated rats [PMID: 17827931]. Leaf extract mitigated acute liver failure and nephrotoxicity in thioacetamide-induced male rats [PMID: 32226246].
Treatment (200-400 mg/kg) in STZ-induced diabetic rats dramatically reduced blood glucose and HbA1c levels and increased SOD and catalase levels [PMID: 37969205].
Used as part of a standalone Ayurveda management regimen in a 34-year-old female case report [PMID: 37865054].
Seed lectin exhibited anti-proliferative activity on nasopharyngeal carcinoma HONE1 cells (IC50 12.8 μM) and slightly inhibited hepatoma growth [PMID: 25240852]. Root compounds (specifically dehydropipernonaline) showed significant bioactivity against prostate (DU-145, PC-3), colon (HT-29), and breast (MCF-7) cancer cell lines [PMID: 39779566].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 37865054 (2023) — Standalone Ayurveda management of Hodgkin's lymphoma: A case report. · Journal of Ayurveda and integrative medicine
- 2.PMID: 39974713 (2024) — Influence of microwave processing on nutritional, anti-nutritional, antioxidant and sensory characteristics of kachnar powder and supplemented flatbreads. · Food chemistry: X
- 3.PMID: 17827931 (2007) — Hepatoprotective properties of Bauhinia variegata bark extract. · Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- 4.PMID: 37929082 (2023) — Wild Edible Flowers of Western Himalayas: Nutritional Characterization, UHPLC-QTOF-IMS-Based Phytochemical Profiling, Antioxidant Properties, and In Vitro Bioaccessibility of Polyphenols. · ACS omega
- 5.PMID: 35438173 (2022) — Chromosomal-level genome assembly of the orchid tree Bauhinia variegata (Leguminosae; Cercidoideae) supports the allotetraploid origin hypothesis of Bauhinia.