PubMed-compiled information sheet
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Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A randomized, double-blind, placebo-controlled study found that patients treated with homeopathic Arnica montana and Bellis perennis maintained similar hemoglobin levels at 72h postpartum (12.7 vs 12.4) compared to a significant decrease in the placebo group (12.7 vs 11.6; p<0.05) [PMID:16036165].
Extracts reduced blood glucose levels in chicken embryos (in ovo) and induced GLUT4 translocation in vitro [PMID:30314325].
B. perennis extract demonstrated photoprotective and immunomodulatory effects in an in vitro model of human skin keratinocytes [PMID:34175580].
B. perennis showed potential to enhance the osteogenic differentiation of C3H10T1/2 multipotent mesenchymal stem cells into osteoblasts [PMID:38683461].
Oleanane-type triterpene saponins exhibited anti-proliferative activities against HSC-2, HSC-4, and MKN-45 cell lines [PMID:27178360].
Evidence summary
PubMed sources
- 1.PMID: 38067445 (2023) — (Bio)active Compounds in Daisy Flower (Bellis perennis). · Molecules (Basel, Switzerland)
- 2.PMID: 30823150 (2001) — First Occurrence of a Rust Fungus on English Daisy (Bellis perennis) in North America. · Plant disease
- 3.PMID: 38683461 (2024) — Enhanced osteogenic differentiation potential of Arnica montana and Bellis perennis in C3H10T1/2 multipotent mesenchymal stem cells. · Molecular biology reports
- 4.PMID: 30314325 (2018) — Insulin Mimetic Properties of Extracts Prepared from Bellis perennis. · Molecules (Basel, Switzerland)
- 5.PMID: 24617777 (2014) — Isolation of an oleanane-type saponin active from Bellis perennis through antitumor bioassay-guided procedures.