PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Oral administration of PM-EVLPs substantially mitigated experimental colitis in mice by targeting inflamed colon macrophages [PMID:40685348].
Wu-Mei-Pill (WMP) and Wu Mei Wan (WMW) demonstrated therapeutic impacts on tumor number, tumor load, and cancer stemness in mouse models [PMID:38452403, PMID:39489363].
A 70% ethanol extract of P. mume bark induced vasorelaxant effects in rat thoracic aortic rings and hypotensive effects in spontaneous hypertensive rats [PMID:36671646]. Infused juice concentrate (bainiku-ekisu) attenuated inflammatory vascular remodeling in Angiotensin II-induced hypertensive mice [PMID:37308550].
Purified polyphenols (L1) showed anticancer activity against HeLa, HepG2, MCF-7, and A549 cell lines [PMID:37092717].
In a human study of participants over 60, serum osteocalcin (OCN) levels were significantly higher in the high ume intake group compared to the low intake group [PMID:35150233].
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 40685348 (2025) — Prunus mume derived extracellular vesicle-like particles alleviate experimental colitis via disrupting NEK7-NLRP3 interaction and inflammasome activation. · Journal of nanobiotechnology
- 2.PMID: 38452403 (2024) — Mechanic evaluation of Wu-Mei-Pill on colitis-associated colorectal cancer: An integrated transcriptomics, metabolomics, and experimental validation study. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 3.PMID: 31491438 (2020) — Anticancer properties of Prunus mume extracts (Chinese plum, Japanese apricot). · Journal of ethnopharmacology
- 4.PMID: 23271652 (2012) — The genome of Prunus mume. · Nature communications
- 5.PMID: 33310179 (2021)