PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 19 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
High doses produce euphoria, hallucinations, sedation, and perceptual disturbances [PMID:34345890].
Hydro-ethanolic extract of the whole flower demonstrated apoptotic properties in vitro [PMID:38285776].
Nuciferine significantly improved neurological deficit scores and ameliorated cerebral edema and infarction [PMID:33403305].
Nuciferine overcame resistance to paclitaxel, doxorubicin, docetaxel, and daunorubicin in HCT-8/T and A549/T cancer cells and suppressed tumor growth in xenograft mice [PMID:32992085].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 34345890 (2023) — Toxicity From Blue Lotus (Nymphaea caerulea) After Ingestion or Inhalation: A Case Series. · Military medicine
- 2.PMID: 38285776 (2024) — The Apoptotic Property of Nymphaea Caerulea Flower Extract on Acute Myeloid Leukaemia Cell Line, THP-1. · Asian Pacific journal of cancer prevention : APJCP
- 3.PMID: 42092166 (2026) — Water lily complete genomes illuminate the innovations of water lilies and early angiosperms. · Nature plants
- 4.PMID: 37894493 (2023) — Chemical Composition, Market Survey, and Safety Assessment of Blue Lotus (Nymphaea caerulea Savigny) Extracts. · Molecules (Basel, Switzerland)
- 5.PMID: 18534639 (2008) — Antioxidant constituents of Nymphaea caerulea flowers.