PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ethanol extract of breadfruit leaves protected Wistar rats against trichloroethylene-induced nephrotoxicity [PMID:42178079]
Water extract of Artocarpus altilis leaves ameliorated isoproterenol-induced myocardial damage in rats [PMID:35125088]
Leaf extracts exhibit in vitro activity against P. falciparum and in vivo activity against P. berghei [PMID:36565667]
Methanol extract significantly reduced relative weight of liver and heart and lowered lipid parameters in rats [PMID:24592277]
Ethyl acetate fractions of leaves were evaluated for diuretic effects in normotensive Wistar rats [PMID:37467570]
Evidence summary
PubMed sources
- 1.PMID: 37006932 (2023) — Breadfruit (Artocarpus altilis): Processing, nutritional quality, and food applications. · Frontiers in nutrition
- 2.PMID: 37765449 (2023) — Total Flavonoid Contents and the Expression of Flavonoid Biosynthetic Genes in Breadfruit (Artocarpus altilis) Scions Growing on Lakoocha (Artocarpus lakoocha) Rootstocks. · Plants (Basel, Switzerland)
- 3.PMID: 35125088 (2022) — Artocarpus Altilis (Breadfruit) could Reverse Myocardial Infarction Through the Normalization of the Oxygen Haemoglobin Dissociation Curve. · Cardiovascular & hematological agents in medicinal chemistry
- 4.PMID: 42178079 (2026) — The protective effects of phenolic-rich breadfruit (Artocarpus altilis) ethanol extract against trichloroethylene-induced nephrotoxicity: In vivo and in silico studies. · Journal of ethnopharmacology
- 5.PMID: 20526745