PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Leaf gel extracts increase tensile strength and protein and DNA content in pig dermal wounds [PMID:23078885, PMID:20937372].
Methanolic and hexane extracts significantly decreased cell viability and induced G1 phase cell cycle arrest in MDA-MB-231 and T47D cells [PMID:31442552].
Isofuranonaphthoquinone showed significant antiproliferative effects comparable to the drug 1,3-bis(2-chloroethyl)-1-nitrosourea [PMID:24575413].
Joziknipholones A and B demonstrated activity against the chloroquine-resistant strain K1 of the malaria pathogen [PMID:18067107].
In vitro profiling was conducted to assess glucose-lowering capabilities, including inhibition of alpha-amylase and alpha-glucosidase [PMID:34919745].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 34919745 (2023) — In vitro profiling and functional assessments of the anti-diabetic capacity of phenolic-rich extracts of Bulbine natalensis and Bulbine frutescens. · Diabetic medicine : a journal of the British Diabetic Association
- 2.PMID: 23078885 (2012) — Bulbine natalensis and Bulbine frutescens promote cutaneous wound healing. · Journal of ethnopharmacology
- 3.PMID: 32492493 (2020) — Ethnobotany, phytochemistry and pharmacological significance of the genus Bulbine (Asphodelaceae). · Journal of ethnopharmacology
- 4.PMID: 20937372 (2011) — A biochemical comparison of the in vivo effects of Bulbine frutescens and Bulbine natalensis on cutaneous wound healing. · Journal of ethnopharmacology
- 5.PMID: 41095187