PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A multi-center, double-blind, randomized placebo-controlled trial in 166 women found that Ruscus aculeatus extract was used to treat lower leg edema [PMID:12040966].
A case report suggests R. aculeatus may be an effective and safe treatment for OH due to its vasoconstrictive properties [PMID:11152059].
In an observational study of 780 patients with venous ulcers, the highest rate of patient satisfaction (51.4%) was found in the group taking Ruscus aculeatus combined with HMC and ascorbic acid [PMID:26406967].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 11152059 (2000) — Ruscus aculeatus (butcher's broom) as a potential treatment for orthostatic hypotension, with a case report. · Journal of alternative and complementary medicine (New York, N.Y.)
- 2.PMID: 27825178 (2016) — Ruscus Genus: A Rich Source of Bioactive Steroidal Saponins. · Planta medica
- 3.PMID: 39419127 (2024) — Herbal drugs in chronic venous disease treatment: An update. · Fitoterapia
- 4.PMID: 12040966 (2002) — Efficacy and safety of a Butcher's broom preparation (Ruscus aculeatus L. extract) compared to placebo in patients suffering from chronic venous insufficiency. · Arzneimittel-Forschung
- 5.PMID: 41302473 (2025) — Current Insights into the Phytochemistry and Pharmacological Properties of Ruscus aculeatus.