PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Pippali Rasayana (containing Butea monosperma and Piper longum) led to the disappearance of G. lamblia from stools in 23 out of 25 patients [PMID:9201614]
Bark extract significantly reduced blood glucose (40.79%) and increased plasma insulin (37.5%) in STZ-induced diabetic rats [PMID:24617860]
Ethyl acetate fraction of bark showed protective effects against thioacetamide-induced pathophysiology in rats, normalizing serum bilirubin, SGOT, SGPT, albumin, and ALP [PMID:28237915]
Ethanol extract demonstrated nephroprotective potential in gentamicin-induced toxicity models in albino rats [PMID:24550595]
A triterpene (TBM) from flowers exhibited anticonvulsant activity against MES, PTZ, electrical kindling, and Li-Pilo induced seizures in animals [PMID:12062587]
Evidence summary
PubMed sources
- 1.PMID: 8241931 (1993) — The quest for a herbal contraceptive. · The National medical journal of India
- 2.PMID: 39736959 (2024) — Butea monosperma as a collective phytomedicine and environmentally sustainable, conservative, and beneficial plant. · Archives of Razi Institute
- 3.PMID: 31605258 (2020) — Awareness and current knowledge of epilepsy. · Metabolic brain disease
- 4.PMID: 29796216 (2018) — Medicinal herbs in the treatment of neuropathic pain: a review. · Iranian journal of basic medical sciences
- 5.PMID: 38723523 (2024) — SIRT1-activating butein inhibits arecoline-induced mitochondrial dysfunction through PGC1α and MTP18 in oral cancer.