This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.
Physostigma venenosum
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
West African legume historically used as ordeal poison by the Efik people of Nigeria, now source of physostigmine for glaucoma and Alzheimer treatment.
West African legume historically used as ordeal poison by the Efik people of Nigeria, now source of physostigmine for glaucoma and Alzheimer treatment. Key active compounds include physostigmine, eserine, calabarine.
physostigmine, along with eserine and calabarine, are the primary bioactive compounds in Calabar Bean. The specific pharmacological pathways require further study, though traditional use supports its efficacy.
Acetylcholinesterase inhibition (pharmaceutical source)
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Glaucoma treatment (pharmaceutical)
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Alzheimer research
Ordeal trial poison in Efik Nigerian tradition
Based on traditional use; clinical evidence limited
Death penalty execution in some West African societies
Based on traditional use; clinical evidence limited
Wound and snake bite in limited folk use
Based on traditional use; clinical evidence limited
Found an error or have a correction for Calabar Bean?
Report an Issue →