PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 6 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
The isolated lectin CasuL demonstrated cytotoxicity with IC50 values of 67.04±5.78µg/mL for K562 cells and 58.75±2.5µg/mL for T47D cells [PMID:28174088].
CasuL inhibited the growth of Staphylococcus isolates (MIC 3.75 to 15 µg/ml) and showed synergistic effects when combined with tetracycline or ampicillin [PMID:31099495].
Biosynthesized silver nanoparticles using C. surinamensis leaf extract showed strong antibacterial properties with a zone of inhibition of 19.09 mm [PMID:38744691].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 41751987 (2026) — Genus Calliandra-Calliandra portoricensis, Calliandra haematocephala, Calliandra surinamensis: A Journey from Traditional Knowledge to Modern Experimental Studies in Disease Prevention and Treatment. · International journal of molecular sciences
- 2.PMID: 28174088 (2017) — CasuL: A new lectin isolated from Calliandra surinamensis leaf pinnulae with cytotoxicity to cancer cells, antimicrobial activity and antibiofilm effect. · International journal of biological macromolecules
- 3.PMID: 31099495 (2019) — Looking for alternative treatments for bovine and caprine mastitis: Evaluation of the potential of Calliandra surinamensis leaf pinnulae lectin (CasuL), both alone and in combination with antibiotics. · MicrobiologyOpen
- 4.PMID: 38744691 (2024) — Biosynthesized silver nanoparticles prevent bacterial infection in chicken egg model and mitigate biofilm formation on medical catheters. · Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry