PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Camellia japonica radix (CJR) demonstrated potential to alleviate oxidative stress and modulate gut microbiota in mouse models [PMID:40334428]
Topical application of extract in SKH-1 mice reduced epidermal thickness, mast cell infiltration, and oxidative stress markers (ROS, NO) [PMID:40806419]
Flower extracts and hyperoside reduced ROS and reversed senescence markers in human skin fibroblasts [PMID:40867864]; flower extracts decreased UVA-induced MMP-1 secretion in keratinocytes [PMID:35072988]
Camellia japonica exhibited high xanthine oxidase inhibitory activity [PMID:37828678]
Fruit shell extract increased proliferation of hair follicle dermal papilla cells and mitigated DHT-induced hair loss in vitro [PMID:36411959]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 39720636 (2024) — Evolutionary Histories of Camellia japonica and Camellia rusticana. · Ecology and evolution
- 2.PMID: 38296496 (2024) — [Dynamic Chemistry of Tannins]. · Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- 3.PMID: 40334428 (2025) — Camellia Japonica Radix modulates gut microbiota and 9(S)-HpODE-mediated ferroptosis to alleviate oxidative stress against MASLD. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 4.PMID: 33918918 (2021) — A Review on the Biological Activity of Camellia Species. · Molecules (Basel, Switzerland)
- 5.PMID: 40867864 (2025) — Camellia japonica Flower Extract and the Active Constituent Hyperoside Repair DNA Damage Through FUNDC1-Mediated Mitophagy Pathway for Skin Anti-Aging.