PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 18 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Specific diterpenes (caryopincaolide 1, 3, and 4) inhibited the growth of human cancer cells, with compound 1 inducing apoptosis in Hey and A-549 cells [PMID:26952788].
An ethyl acetate fraction of aerial parts showed cytoprotective effects against tert-butylhydroperoxide-induced damage in human HepG2 cells [PMID:24582277].
Extracts showed growth inhibition of Streptococcus mutans [PMID:31597167] and moderate antimicrobial activity against Bacillus subtilis [PMID:23771561].
Extracts from leaves and stems inhibited angiogenesis by more than 50% in a quail egg CAM assay [PMID:23970927].
Evidence summary
PubMed sources
- 1.PMID: 38759829 (2024) — Abietane diterpenoids from Caryopteris incana (Thunb.) Miq. And their HIF-2α inhibitory activities in vitro. · Phytochemistry
- 2.PMID: 26952788 (2016) — Abietane diterpenoids from Caryopteris incana (Thunb.) Miq. · Organic & biomolecular chemistry
- 3.PMID: 23771561 (2014) — Constituents of Caryopteris incana and their antibacterial activity. · Journal of natural medicines
- 4.PMID: 40573828 (2025) — Intraspecific Evaluation of Phenotypic Variations of Caryopteris incana (Thunb. ex Houtt.) Miq. in Western Kyushu, Japan. · Plants (Basel, Switzerland)
- 5.PMID: 30474771 (2019) — Caryopincaolide M, a rearranged abietane diterpenoid with new skeleton and a new iridoid from Caryopteris incana.