PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Fruit flavanol preparations inhibit SW-480 cell viability and suppress COX-2 and MMP-9 expression [PMID:28787469]. Leaf phenol-rich extracts inhibit migration and invasion in SW-480 and HT-29 cells [PMID:35639036].
Leaf polyphenol-rich extract decreases expression of Nfkb1, Ptgs2, and Il1b in LPS-activated murine macrophages [PMID:33727430].
Fruit polyphenolic extract increases glucose uptake and glycogen content in HepG2 cells via AMPK activation [PMID:29494709].
Fruit extracts from specific cultivars demonstrate antimicrobial activity against three Gram-positive and three Gram-negative bacteria and one yeast strain [PMID:32824623].
Evidence summary
PubMed sources
- 1.PMID: 38062238 (2023) — Phytochemistry and pharmacology of plants in the genus Chaenomeles. · Archives of pharmacal research
- 2.PMID: 36969921 (2023) — Phytochemical characterization of oil and protein fractions isolated from Japanese quince (Chaenomeles japonica) wine by-product. · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire
- 3.PMID: 40282771 (2025) — The Concentrations of Phenolic Compounds and Vitamin C in Japanese Quince (Chaenomeles japonica) Preserves. · Foods (Basel, Switzerland)
- 4.PMID: 32586126 (2022) — Profiling of the lipophilic components of seed oils recovered from twelve Japanese quince (Chaenomeles japonica) genotypes. · Natural product research
- 5.PMID: 35639036