PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Fruit ethanol extract ameliorated hyperglycemia and elevated blood pressure in streptozotocin-induced diabetic rats via modulation of oxidative stress, NF-κB, and PPAR-γ [PMID:34225016]. Fruit pulp powder influenced Nrf2, SOD, CAT, and GST expressions in diabetic rats [PMID:34900818].
A fruit-supplemented diet enhanced cognitive functions and attenuated lipopolysaccharide-induced memory impairment and oxidative stress in mice [PMID:38624427]. Fruit extract showed neuroprotective effects against stress and LPS-induced behavioral impairments in mice [PMID:35867181].
Diet supplemented with fruit pulp improved sperm parameters, reproductive hormones, and antioxidant markers in hypertensive male rats [PMID:34591290].
Seed and pulp extracts demonstrated both suppressive and curative antimalarial properties in Albino mice inoculated with Plasmodium berghei [PMID:29269970].
Fruit peel extract significantly reduced abdominal writhing and paw edema in rodent models by inhibiting pro-inflammatory cytokines and COX-2 [PMID:32375072]. Seed oil demonstrated anti-inflammatory effects in carrageenan-induced acute inflammation and CFA-induced arthritis [PMID:42036000].
Safety & adverse effects
Pregnancy & lactation
Evidence summary
PubMed sources
- 1.PMID: 33270256 (2021) — Bioactive compounds of African star apple (Chrysophyllum albidum G. Don) and its modulatory effect on metabolic activities linked to type 2 diabetes in isolated rat psoas muscle. · Journal of food biochemistry
- 2.PMID: 38624427 (2020) — Chrysophyllum albidum (African star apple) fruit-supplemented diet enhances cognitive functions and attenuates lipopolysaccharide-induced memory impairment, oxidative stress, and release of proinflammatory cytokines. · Nutrire : revista de Sociedade Brasileira de Alimentacao e Nutricao = journal of the Brazilian Society of Food and Nutrition
- 3.PMID: 36765149 (2023) — Ecological niche model transferability of the white star apple (Chrysophyllum albidum G. Don) in the context of climate and global changes. · Scientific reports
- 4.PMID: 23046832 (2012) — Ethno-botanical study of the African star apple (Chrysophyllum albidum G. Don) in the Southern Benin (West Africa). · Journal of ethnobiology and ethnomedicine
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