PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 20 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Used as one of nine ingredients in the traditional Sri Lankan decoction Pitawakka Navaya to treat chronic sinusitis [PMID:22131709].
Ethanolic root extract attenuated inflammatory mediators and biomarkers in ovalbumin-induced rat models [PMID:38143476].
Standardized aqueous extracts demonstrated anti-inflammatory and anti-arthritic potential [PMID:33912046].
Ursolic acid isolated from roots showed significant hepatoprotective activity against carbon tetrachloride-induced toxicity in rats [PMID:17585689].
Leaf extract (specifically flavonoids apigenin and luteolin) showed neuroprotective effects against acute restraint stress-induced symptoms in mice [PMID:28458420].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 24727551 (2014) — Clerodendrum serratum (L.) Moon. - a review on traditional uses, phytochemistry and pharmacological activities. · Journal of ethnopharmacology
- 2.PMID: 38143476 (2022) — Clerodendrum serratum extract attenuates production of inflammatory mediators in ovalbumin-induced asthma in rats. · Turkish journal of chemistry
- 3.PMID: 40812437 (2025) — Mechanistic evaluation of Clerodendrum serratum anti-biofilm potency against Mycobacterium species. · Microbial pathogenesis
- 4.PMID: 23284214 (2012) — Anti-histaminic, mast cell stabilizing and bronchodilator effect of hydroalcoholic extract of polyherbal compound- Bharangyadi. · Ancient science of life
- 5.PMID: 22131709 (2010)