PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 7 PubMed articles · model: gemma4:31b
Summary
Colchicum speciosum is a perennial stemless flowering herb native to northern Turkey, the Caucasus, and northern Iran [PMID:35262800].
Background
Colchicum speciosum Steven is a perennial stemless plant native to the mountainous regions of northern Turkey, the Caucasus, and northern Iran, known locally as 'Vargit, Aç iğdem, Güz iğdemi' [PMID:35262800].
Active compounds
The seeds of Colchicum speciosum contain colchicine (75.9 mg/100 g) and colchicoside (51.9 mg/100 g) [PMID:27169190].
Clinical evidence
Evidence DMicrobial infections
Methanol extracts of the corm and leaf demonstrated antimicrobial activity, specifically against C. tropicalis ATCC 750 with a MIC value of 160 µg/mL [PMID:35262800]
Evidence DDiabetes (enzyme inhibition)
Methanol extracts of the corm, leaf, and flower exhibit α-amylase and α-glucosidase inhibitory activities [PMID:35262800]
Evidence DOxidative stress
Methanol extracts of the corm, leaf, and flower demonstrate antioxidant activities [PMID:35262800]
Evidence summary
The available evidence is limited to preliminary in vitro screenings and phytochemical analyses (Level D), primarily focusing on antimicrobial, antioxidant, and antidiabetic enzyme inhibition.
PubMed sources
- 1.PMID: 35262800 (2022) — Screening of antimicrobial, antioxidant, antidiabetic activities, anatomical and morphological properties of Colchicum speciosum Steven (Colchicaceae). · Protoplasma
- 2.PMID: 27169190 (2016) — Comparison of Seeds of Colchicum speciosum and Gloriosa superba in respect to Colchicine and Colchicoside Contents by RP-LC. · Natural product communications