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Vaccinium macrocarpon
This herb may interact with medications you are taking. Review the interactions table below and consult your healthcare provider before use.
Cranberry is a North American native fruit widely recognized for its role in urinary tract health. It contains proanthocyanidins (PACs) that prevent bacteria from adhering to urinary tract walls. Cranberry is one of the best-studied botanicals for UTI prevention and is recommended by many healthcare practitioners.
Cranberry (Vaccinium macrocarpon) is the only herb with Level A evidence for UTI prevention. Proanthocyanidins prevent bacterial adhesion to uroepithelial cells.
A-type proanthocyanidins (PACs) inhibit P-fimbriae adhesion of E. coli. Minimum effective dose is 36mg PACs daily. Also acidifies urine slightly.
UTI prevention
Cochrane: 30-35% reduction in recurrence
UTI treatment
Not effective for active infection
Bacterial anti-adhesion
Well-documented mechanism
| Drug | Severity | Description |
|---|---|---|
| Warfarin (Coumadin) | Moderate | Cranberry products may increase the anticoagulant effect of warfarin. Several cases of increased INR and bleeding have been reported, including one fatality. |
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