PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 14 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
The isolated saponin nummularoside showed significant activity against prostate cancer cells (EC50 1.2 and 7.4 μg/mL) and glioblastoma cells (EC50 6.0 μg/mL), while showing less effect on normal cells [PMID:23665578].
Evidence summary
PubMed sources
- 1.PMID: 42098972 (2026) — Morpho-Anatomical and HPTLC Investigations of Lysimachia nummularia L. (Primulaceae) Grown in Switzerland. · Microscopy research and technique
- 2.PMID: 27104751 (2016) — A new ultra-high pressure liquid chromatography method for the determination of antioxidant flavonol aglycones in six Lysimachia species. · Natural product research
- 3.PMID: 23665578 (2013) — A new cytotoxic triterpene saponin from Lysimachia nummularia L. · Carbohydrate research
- 4.PMID: 32085594 (2020) — Cytotoxic, Antimicrobial, Antioxidant Properties and Effects on Cell Migration of Phenolic Compounds of Selected Transylvanian Medicinal Plants. · Antioxidants (Basel, Switzerland)
- 5.PMID: 26415274 (2015)