PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Active compounds
Mechanism of action
Clinical evidence
Six cucurbitacin C analogues showed growth inhibition against HepG2, A549, DU145, and HCT116 cell lines; specifically, cucurbitacin C6 and C7 exhibited significant inhibition of the HepG2 cell line [PMID:35182783]
Transgenic cucumber expressing poly-γ-glutamic acid demonstrated moisturizing, whitening, and anti-wrinkle effects in zebrafish and human skin experiments, reducing facial wrinkles by 19.58% and melanin content by 5.27% [PMID:38336313]
Evidence summary
PubMed sources
- 1.PMID: 30253288 (2019) — Molecular basis of cucumber fruit domestication. · Current opinion in plant biology
- 2.PMID: 35182783 (2022) — Identification of seven undescribed cucurbitacins in Cucumis sativus (cucumber) and their cytotoxic activity. · Phytochemistry
- 3.PMID: 36616152 (2022) — Morphological and Genetic Diversity of Cucumber (Cucumis sativus L.) Fruit Development. · Plants (Basel, Switzerland)
- 4.PMID: 38768880 (2024) — Oxylipin biosynthesis via an unprecedented 16-hydroperoxide lyase pathway in green tissues of cucumber (Cucumis sativus L.) plants. · Phytochemistry
- 5.PMID: 32347059 (2020) — [Advances in Agrobacterium tumefaciens-mediated transgenic cucumber].