PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ecdysteroid-enriched fractions reduced arthritis scores and paw swelling in rats and suppressed synovial proliferation and inflammation [PMID:40257367].
Root extracts inhibited arterial remodeling in spontaneously hypertensive rats [PMID:29285068].
Cyaonoside A resisted IL-1β-mediated chondrogenic inflammation and apoptosis and increased expression of cartilage-specific genes (ACAN, COL2A, SOX9) [PMID:39908269, 38591180].
Extracts improved blood rheology and exhibited anti-inflammatory properties in acute blood stasis rat models [PMID:29200735].
Phosphorylated polysaccharides increased serum immunoglobulin concentrations and enhanced T cell subpopulations in immunosuppressed mice [PMID:31731832].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 40777991 (2025) — Effects and molecular mechanisms of Achyranthes bidentata Blume and Cyathula officinalis K.C. Kuan in the treatment of rheumatoid arthritis. · Frontiers in pharmacology
- 2.PMID: 35850203 (2022) — The complete chloroplast genome sequence of Cyathula officinalis and comparative analysis with four related species. · Gene
- 3.PMID: 38243389 (2024) — Oligo/polysaccharides from Cyathula officinalis and Achyranthes bidentata: a review of structures and bioactivities. · The Journal of pharmacy and pharmacology
- 4.PMID: 35065449 (2022) — Undescribed ecdysteroids and phenolic glycosides from the roots of Cyathula officinalis Kuan and their anti-inflammatory activity in LPS-induced RAW 264.7 macrophages in vitro. · Phytochemistry
- 5.PMID: 34432202