PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Meals containing Detarium senegalense flour (rich in water-soluble NSP) reduced postprandial blood glucose and insulin concentrations in healthy human subjects compared to controls [PMID:9924263]
Ethanolic extracts of D. senegalense demonstrated in vitro antibacterial and antibiofilm activities (biofilm inhibition > 50%) and in vivo antibacterial potential in a rat model [PMID:36521244]
Computational investigation identified catechin, epicatechin, and gallic acid as leading compounds with significant binding affinities for enzymes implicated in ED, including PDE5 [PMID:39596427]
Evidence summary
PubMed sources
- 1.PMID: 39596427 (2024) — Computational Investigation of the Therapeutic Potential of Detarium senegalense in the Management of Erectile Dysfunction. · International journal of molecular sciences
- 2.PMID: 36262304 (2022) — Influence of morphological characteristics of fruits and provenances on seedling emergence and early growth in Detarium microcarpum Guill. & Perr. and Detarium senegalense J.F. Gmel. (Fabaceae) in Benin. · Heliyon
- 3.PMID: 36521244 (2023) — Anti-Salmonella activity of plant species in the Benin republic: Artemisia afra and Detarium senegalense with promising in vitro and in vivo activities. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- 4.PMID: 8653722 (1996) — A new polysaccharide from a traditional Nigerian plant food: Detarium senegalense Gmelin. · Carbohydrate research
- 5.PMID: 9924263