PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A 40% ethanolic extract accelerated wound healing by modulating IL-10 and MCP-1 release and increasing collagen synthesis [PMID:37111271].
Inhibiting effects on the elevation of triglyceride and cholesterol were observed in both high and low doses [PMID:8323687].
Ethanol extracts and their partitions demonstrated antiproliferative activity in human oral tumor lines SCC-9, SCC4, and SCC-25 [PMID:36535330].
Exerted significant antiproliferative effects in a dose- and time-dependent manner [PMID:23000169].
A bioactive glass-carbon material (BG-Carb) derived from E. hyemale ashes promoted increased bone formation at 7 days compared to hyaluronan alone [PMID:41212454].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 37111271 (2023) — Horsetail (Equisetum hyemale) Extract Accelerates Wound Healing in Diabetic Rats by Modulating IL-10 and MCP-1 Release and Collagen Synthesis. · Pharmaceuticals (Basel, Switzerland)
- 2.PMID: 36535330 (2023) — New substances of Equisetum hyemale L. extracts and their in vivo antitumoral effect against oral squamous cell carcinoma. · Journal of ethnopharmacology
- 3.PMID: 36303438 (2022) — Heavy metal accumulation efficiency and subsequent of cytogenotoxicity evaluation in the medicinal plant Equisetum hyemale. · Journal of toxicology and environmental health. Part A
- 4.PMID: 41471390 (2025) — Equisetum hyemale L. Extracts: Phytochemistry, Biological Performance, ADMET Profiling, and Toxicity Predictions. · Pharmaceuticals (Basel, Switzerland)
- 5.PMID: 25117054