PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A single-blind randomized clinical trial compared E. platyloba extract, fennel extract, and placebo in students with moderate to severe PMS [PMID:23926506]. A systematic review of Iranian herbal medicines for PMS included E. platyloba as an effective treatment [PMID:29632841].
Ethanolic extract showed a potent synergistic effect when combined with itraconazole and fluconazole against clinical isolates from women with chronic recurrent vaginitis [PMID:24746726].
Safety & adverse effects
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 30018233 (2018) — TRPA1 Modulating C14 Polyacetylenes from the Iranian Endemic Plant Echinophora platyloba. · Molecules (Basel, Switzerland)
- 2.PMID: 23926506 (2011) — Comparing the Effects of Echinophora-platyloba, Fennel and Placebo on Pre-menstrual Syndrome. · Journal of reproduction & infertility
- 3.PMID: 22666795 (2012) — Acute and subchronic toxicological evaluation of Echinophora platyloba DC (Apiaceae) total extract in Wistar rats. · Clinics (Sao Paulo, Brazil)
- 4.PMID: 27054002 (2016) — Evaluation the antibacterial effects of Echinophora platyloba extracts against some Salmonella species. · Electronic physician
- 5.PMID: 27182677 (2016) — Antifungal effect of Echinophora platyloba on expression of CDR1 and CDR2 genes in fluconazole-resistant Candida albicans.