PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Standardized aqueous extract induced hypotension in normotensive rats and decreased hypertension in spontaneous hypertensive rats and L-NAME induced models [PMID:17446057]
Crude aqueous extract demonstrated in vivo anti-inflammatory effects in a pleurisy animal model, reducing proinflammatory cytokines (TNF-α, IL-1β, and IL-6) [PMID:26965365]
Hydroethanolic extract (20 mg/kg) showed hepatoprotective effects by inhibiting lipid peroxidation and decreasing serum ALT and AST levels in CCl4-induced models [PMID:22480215]
C-glycosylflavonoid-enriched fractions showed in vitro anti-herpes activity by inhibiting virus entry and reducing viral infectivity [PMID:20572924, PMID:22480215]
Standardized aqueous extract inhibits gastric acid secretion [PMID:18462931]
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 26965365 (2016) — Anti-inflammatory and antioxidant activities of aqueous extract of Cecropia glaziovii leaves. · Journal of ethnopharmacology
- 2.PMID: 32786546 (2020) — Effects of Standardized Medicinal Plant Extracts on Drug Metabolism Mediated by CYP3A4 and CYP2D6 Enzymes. · Chemical research in toxicology
- 3.PMID: 18462931 (2008) — Inhibition of gastric acid secretion by a standardized aqueous extract of Cecropia glaziovii Sneth and underlying mechanism. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 4.PMID: 22480215 (2012) — Hepatoprotective effects and HSV-1 activity of the hydroethanolic extract of Cecropia glaziovii (embaúba-vermelha) against acyclovir-resistant strain. · Pharmaceutical biology
- 5.PMID: 34610498