PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Sulfated polysaccharide extract exhibited specific cytotoxicity against human hepatocellular Hep G2 carcinoma cells [PMID:32482099]. Methanolic leaf extract showed significant growth inhibition in HeLa (IC50 2.07 µg/mL) and MCF7 (IC50 11.84 µg/mL) cell lines [PMID:25460593].
Extracts demonstrated interesting antifungal activities and are considered candidates for antifungal formulations [PMID:23280633].
Hydroalcoholic extracts of fruits showed an ovicidal effect close to 100% against Haemonchus contortus eggs at 100 mg/mL [PMID:38232035].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 35780973 (2022) — Experimental intoxication of Brahman (Bos indicus) heifers with Enterolobium cyclocarpum fruits. · Toxicon : official journal of the International Society on Toxinology
- 2.PMID: 32482099 (2021) — Cancer Chemopreventive Properties of Sulfated Enterolobium cyclocarpum Extract. · Nutrition and cancer
- 3.PMID: 19945990 (2010) — The impact of landscape disturbance on spatial genetic structure in the Guanacaste tree, Enterolobium cyclocarpum (Fabaceae). · The Journal of heredity
- 4.PMID: 21669693 (2001) — Variation in the breeding behavior of the dry forest tree Enterolobium cyclocarpum (guanacaste) in Costa Rica. · American journal of botany
- 5.PMID: 25460593 (2015)