This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.
Zanthoxylum zanthoxyloides
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
The roots of the African prickly ash tree used in West African traditional medicine for sickle cell disease.
The roots of the African prickly ash tree used in West African traditional medicine for sickle cell disease. Key active compounds include fagaronine, benzophenanthridine alkaloids, zanthoxylum.
fagaronine, along with benzophenanthridine alkaloids and zanthoxylum, are the primary bioactive compounds in Fagara Root. These compounds modulates NF-κB and COX-2 inflammatory pathways, disrupts microbial cell membranes and inhibits pathogen growth, acts on pain pathways via anti-inflammatory and neuroactive effects.
Antisickling
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Analgesic
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Antimicrobial
Anti-inflammatory
Sickle cell disease
Based on traditional use; clinical evidence limited
Pain
Based on traditional use; clinical evidence limited
Infections
Based on traditional use; clinical evidence limited
Fever
Based on traditional use; clinical evidence limited
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