PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Administration in rat models improved body weight and reduced synovial tissue pathology and serum inflammatory factors [PMID:37285946]; aqueous extracts act on TNF-α and RAGE signaling pathways [PMID:40688514].
Methanol extract of the root significantly decreased nitric oxide and inflammatory cytokine levels in DSS-induced colitis mouse models [PMID:38024289].
A decoction of Schizonepeta tenuifolia and Saposhnikovia divaricata alleviated atopic dermatitis-like symptoms in mice by downregulating macrophage TRPV1 [PMID:39257398].
YuPingFengSan (containing S. divaricata) ameliorates LPS-induced acute lung injury and gut barrier dysfunction in mice [PMID:37019161].
Topical essential oil of S. divaricata mitigated Cutibacterium acnes-induced inflammatory acne in mouse ears [PMID:41015324].
Evidence summary
PubMed sources
- 1.PMID: 37019161 (2023) — YuPingFengSan ameliorates LPS-induced acute lung injury and gut barrier dysfunction in mice. · Journal of ethnopharmacology
- 2.PMID: 32328867 (2020) — Saposhnikovia divaricata-An Ethnopharmacological, Phytochemical and Pharmacological Review. · Chinese journal of integrative medicine
- 3.PMID: 39257398 (2024) — Schizonepeta tenuifolia Briq-Saposhnikovia divaricata decoction alleviates atopic dermatitis via downregulating macrophage TRPV1. · Frontiers in pharmacology
- 4.PMID: 37733271 (2023) — Advances in Phytochemistry and Modern Pharmacology of Saposhnikovia Divaricata (Turcz.) Schischk. · Chinese journal of integrative medicine
- 5.PMID: 35627316 (2022)