PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 29 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Aqueous and alcoholic extracts of the leaf significantly reduced blood glucose concentrations in normal and alloxan-induced diabetic rats [PMID:9421250].
Aqueous and ethanolic leaf extracts, as well as a 30% aqueous gel formulation, exhibited activity against Malassezia furfur, Aspergillus niger, and Candida albicans [PMID:31524496].
Fenugreek leaf extract was investigated for its effects on behavioral and cognitive function, oxidative stress markers, and Aβ-42 aggregates in transgenic flies [PMID:40785177].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 33378775 (2021) — Recent Therapeutic Interventions of Fenugreek Seed: A Mechanistic Approach. · Drug research
- 2.PMID: 42237037 (2026) — Identification of candidate genes governing key metabolic pathways in fenugreek (Trigonella spp.) through integrated transcriptomic and metabolomic analysis. · Functional & integrative genomics
- 3.PMID: 35816152 (2023) — Underutilized green leafy vegetables: frontier in fortified food development and nutrition. · Critical reviews in food science and nutrition
- 4.PMID: 31524496 (2020) — Fenugreek Leaf Extract and Its Gel Formulation Show Activity Against Malassezia furfur. · Assay and drug development technologies
- 5.PMID: 9421250 (1997)