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This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Ficus benghalensis, commonly known as the Indian Banyan, is a medicinal plant from the Moraceae family used in traditional Indian medicine for various therapeutic purposes [PMID:39106616, PMID:34961220].
Background
Ficus benghalensis is a large woody tree characterized by extraordinary aerial roots and is considered the national tree of India [PMID:36164650, PMID:19580111]. It is widely distributed across Asian countries, including Malaysia and Nepal [PMID:34961220, PMID:27809820].
Traditional uses
Traditionally, it is indicated for the treatment of diabetes mellitus, dysentery, leucorrhoea, menorrhagia, skin disease, rheumatism, inflammatory diseases, and blood disorders [PMID:39106616]. In the Ayurvedic Pharmacopeia of India, the bark is recorded for managing burning sensation, obesity, diabetes, bleeding disorders, thirst, skin diseases, wounds, and dysmenorrhoea [PMID:34678414]. Aerial roots are traditionally used to treat female reproductive disorders [PMID:38043752].
Active compounds
The plant contains a rich diversity of bioactive constituents, including phenols, flavonoids (quercetin, kaempferol, apigenin, and leucopelargonidin), alkaloids, tannins, terpenoids (lupeol, α- and β-amyrin acetates, and ursolic acid), steroids (β-sitosterol and stigmasterol), saponins, glycosides, and phenolic acids [PMID:39106616, PMID:34961220, PMID:42255707].
Mechanism of action
The herb exhibits anti-thrombotic actions through anti-coagulant, platelet-antiaggregatory, anti-atherogenic, hypolipidemic, and hypotensive properties [PMID:39106616]. It may promote glucose uptake, with 4-methoxybenzoic acid identified as a potential lead hit for anti-diabetic effects via glucose transporter-2 [PMID:35673455].
Clinical evidence
Evidence DInsulin Resistance
Hydroalcoholic extract of F. benghalensis bark reversed insulin resistance in fructose-induced insulin-resistant rats [PMID:34678414]
Evidence DImmunity
Aqueous extract of aerial roots significantly increased phagocytosis by human neutrophils in vitro and stimulated cell-mediated and antibody-mediated immune responses in rats [PMID:20046734]
Evidence DPain (Analgesia)
Aqueous root extracts were tested in Swiss albino mice using hot-plate, tail-flick, and writhing tests to evaluate antinociceptive paradigms [PMID:27114650]
Evidence DNeurological Parameters
A 200 mg/kg dose of aqueous root extract in mice showed a significant reduction in time spent in the shock-zone during passive-avoidance tests for memory [PMID:27809820]
Evidence summary
The current evidence is primarily based on in vitro studies, animal models (rats and mice), and literature reviews. There are no human clinical trials provided in the abstracts.
PubMed sources
1.PMID: 39106616 (2024) — Therapeutic potential of Ficus benghalensis in thromboembolic disorders. · Journal of Ayurveda and integrative medicine
2.PMID: 34961220 (2021) — Phytochemistry, Pharmacological Properties, and Recent Applications of Ficus benghalensis and Ficus religiosa. · Plants (Basel, Switzerland)
3.PMID: 42255707 (2026) — Pharmacological and Phytochemical Insights Into Ficus benghalensis (Indian Banyan): Anti-Inflammatory, Antioxidant, and Anticancer Potentials. · Food science & nutrition
4.PMID: 27114650 (2016) — Effect of root-extracts of Ficus benghalensis (Banyan) in pain in animal models. · Journal of neurosciences in rural practice
No direct government monograph is available for this herb. The content below is AI-generated and has not been verified against an authoritative government source. Use the search links to check official sources before relying on this information.
— Effect of root-extracts of Ficus benghalensis (Banyan) in memory, anxiety, muscle co-ordination and seizure in animal models.
· BMC complementary and alternative medicine
6.PMID: 36432418 (2022) — Mechanistic Insights into the Neuroprotective Potential of Sacred Ficus Trees. · Nutrients
7.PMID: 34678414 (2022) — Reversal of insulin resistance by Ficus benghalensis bark in fructose-induced insulin-resistant rats. · Journal of ethnopharmacology
8.PMID: 36164650 (2022) — Genome sequencing and comparative analysis of Ficus benghalensis and Ficus religiosa species reveal evolutionary mechanisms of longevity. · iScience
9.PMID: 38043752 (2024) — A metabolomics approach for the evaluation of Ficus benghalensis female in vivo reproductive effects relative to its metabolite fingerprint as determined via UPLC-MS and GC-MS. · Journal of ethnopharmacology
10.PMID: 35673455 (2022) — Ficus benghalensis promotes the glucose uptake- Evidence with in silico and in vitro. · Journal of diabetes and metabolic disorders
11.PMID: 19580111 (2007) — Medico-historical review of Nyagrŏdha (Ficus bengalensis Linn.). · Bulletin of the Indian Institute of History of Medicine (Hyderabad)
12.PMID: 20046734 (2008) — Immunological studies on the aerial roots of the Indian banyan. · Indian journal of pharmaceutical sciences