PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 17 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Methanol extract ameliorated seizure severity, neuronal cell degeneration, and cognitive deficits in PTZ-kindled rats and mice [PMID:38729331, PMID:25636876]. Saponin-rich fractions protected mice against PTZ- and strychnine-induced seizures [PMID:19111909].
Standardized methanol stem bark extract increased hot plate nociceptive and vocalisation thresholds in mice [PMID:26945978].
Extract reversed apomorphine-induced hyperactivity and prepulse inhibition deficits in rats, demonstrating neuroleptic-like properties [PMID:26192913, PMID:12576211].
Aqueous extract was studied for its ability to promote fertility in female Wistar rats [PMID:22046966].
Aqueous stem bark extract demonstrated gastroprotective, antisecretory, and ulcer-healing effects in Wistar rats [PMID:42034173].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 26945978 (2016) — Analgesic potential of standardized methanol stem bark extract of Ficus platyphylla in mice: Mechanisms of action. · Journal of ethnopharmacology
- 2.PMID: 22046966 (2011) — Ficus platyphylla promotes fertility in female Rattus norvegicus Wistar strain: a preliminary study. · Reproductive biology and endocrinology : RB&E
- 3.PMID: 42034173 (2026) — Gastroprotective, antisecretory and ulcer-healing effects of the aqueous stem bark extract of Ficus platyphylla Delile in Wistar rats. · Journal of ethnopharmacology
- 4.PMID: 38729331 (2024) — Ficus platyphylla alleviates seizure severity and neurobehavioral comorbidities in pentylenetetrazole-kindled rats via modulation of oxidative stress. · Brain research
- 5.PMID: 39640650