PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Standardized extracts show promising utility via direct antimicrobial effects against Porphyromonas gingivalis and anti-inflammatory actions [PMID:35306173]
Extracts attenuated neuropathy, displayed hypoglycemic effects, and reduced proinflammatory cytokine levels [PMID:35356266]
Ethyl acetate fraction mitigated these conditions by regulating oxidative inflammatory pathways [PMID:40956519]
Extract attenuated cardiac weight loss and injury by reducing oxidative stress and increasing glutathione, SOD, and catalase [PMID:37452121]
Ethanol extract reduced blood levels of creatinine, urea nitrogen, and malondialdehyde [PMID:38736464]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 28503050 (2017) — Fingerroot, Boesenbergia rotunda and its Aphrodisiac Activity. · Pharmacognosy reviews
- 2.PMID: 35306173 (2022) — Toward the use of Boesenbergia rotunda extracts and the chalcone panduratin A to treat periodontitis. · Journal of oral biosciences
- 3.PMID: 40362555 (2025) — Potential Cutaneous Applications of Boesenbergia rotunda Extract Based on Its In Vitro Anti-Melanogenic and Anti-Fibroproliferative Properties. · International journal of molecular sciences
- 4.PMID: 32270712 (2021) — Cytotoxic Activity of Boesenbergia rotunda Extracts against Nasopharyngeal Carcinoma Cells (HK1). Cardamonin, a Boesenbergia rotunda Constituent, Inhibits Growth and Migration of HK1 Cells by Inducing Caspase-Dependent Apoptosis and G2/M-Phase Arrest. · Nutrition and cancer
- 5.PMID: 17968473