PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 6 PubMed articles · model: gemma4:31b
Summary
Freesia refracta is a perennial flower of the Iridaceae family used in cosmetics for its potential anti-aging skin benefits [PMID:39125720].
Background
Freesia refracta is a perennial flower belonging to the Iris family (Iridaceae) [PMID:39125720].
Active compounds
Analysis of Freesia refracta callus extract (FCE) identified key biologically active compounds, specifically nicotinamide and pyroglutamic acid [PMID:39125720].
Mechanism of action
Freesia refracta callus extract (FCE) increases collagen I production in both normal and aged fibroblasts and enhances the interaction between fibroblasts and collagen [PMID:39125720].
Clinical evidence
Evidence BSkin aging (roughness and collagen density)
A 28-day application of a cream containing 3% FCE in 43 female volunteers resulted in an 11.1% reduction in skin roughness and a 2.3-fold increase in collagen density [PMID:39125720].
Evidence summary
Evidence is limited to a single clinical study (B) and laboratory analysis (D) regarding the topical application of callus extract for skin benefits; other available data focus on plant pathology and botany.
PubMed sources
- 1.PMID: 39125720 (2024) — Analysis of Active Components and Transcriptome of Freesia refracta Callus Extract and Its Effects against Oxidative Stress and Wrinkles in Skin. · International journal of molecular sciences