PubMed-compiled information sheet
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Compiled from 7 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Clinical evidence
Methanol extracts exhibited high in vitro antiplasmodial activity (IC50 < 5 microg/mL) against both chloroquine-sensitive (D6) and resistant (W2) clones [PMID:17486688]. Methanol leaf extracts were also found active (IC50 < 15mug/ml) against chloroquine-sensitive (3D7) and resistant (W2) strains [PMID:20035853].
In vivo studies in mice showed chemosuppression of parasitaemia ranging from 49.64-65.28% [PMID:17486688].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 17486688 (2007) — Antimalarial activity of some plants traditionally used in Meru district of Kenya. · Phytotherapy research : PTR
- 2.PMID: 20035853 (2010) — Antiplasmodial and cytotoxic activities of Rwandan medicinal plants used in the treatment of malaria. · Journal of ethnopharmacology