PubMed-compiled information sheet
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Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
In mouse models of DSS-induced and DNBS-induced colitis, total alkaloid fractions from F. capreolata reduced macroscopic and microscopic signs of intestinal inflammation and restored colonic expression of barrier markers [PMID:32717615, PMID:27387398].
Oral administration of total alkaloid extract from F. capreolata significantly inhibited acetic acid-induced writhes and reduced formalin-induced paw licking in mice [PMID:26351518].
F. capreolata demonstrated significant antioxidant capacity, which correlates with its high flavonoid content [PMID:28420145].
Evidence summary
PubMed sources
- 1.PMID: 32739338 (2020) — Diverse alkaloids and biological activities of Fumaria (Papaveraceae): An ethnomedicinal group. · Fitoterapia
- 2.PMID: 28420145 (2017) — Evaluation of Polyphenolic Content, Antioxidant and Diuretic Activities of Six Fumaria Species. · Molecules (Basel, Switzerland)
- 3.PMID: 32717615 (2020) — Intestinal anti-inflammatory activity of the total alkaloid fraction from Fumaria capreolata in the DSS model of colitis in mice. · Bioorganic & medicinal chemistry letters
- 4.PMID: 26351518 (2015) — Antinociceptive and Anti-Inflammatory Effects of Total Alkaloid Extract from Fumaria capreolata. · Evidence-based complementary and alternative medicine : eCAM
- 5.PMID: 24253694 (1985)