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Gelsemium sempervirens
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
Southeastern US vine; small doses historically used for neuralgia; extremely toxic.
Southeastern US vine; small doses historically used for neuralgia; extremely toxic. Key active compounds include gelsemine, sempervirine, gelseverine.
gelsemine, along with sempervirine and gelseverine, are the primary bioactive compounds in Gelsemium sempervirens. These compounds acts on pain pathways via anti-inflammatory and neuroactive effects.
Historical analgesic - too toxic for modern use
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Neuralgia
Based on traditional use; clinical evidence limited
Migraine
Based on traditional use; clinical evidence limited
Fever historically
Based on traditional use; clinical evidence limited
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