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Ginkgo biloba
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
This herb may interact with medications you are taking. Review the interactions table below and consult your healthcare provider before use.
Ginkgo biloba is one of the oldest living tree species, often referred to as a living fossil. Its leaves have been used in Traditional Chinese Medicine for thousands of years. It is one of the top-selling herbal supplements worldwide, primarily used for cognitive function and circulatory health.
Ginkgo (Ginkgo biloba) is the oldest living tree species with documented medicinal use spanning over 5,000 years. Standardized extracts (24% flavone glycosides, 6% terpene lactones) are among the most studied botanicals for cognitive health.
Ginkgolides are potent PAF antagonists, reducing platelet aggregation. Bilobalide protects mitochondrial function. Flavonoids scavenge free radicals. Also modulates neurotransmitter systems and increases BDNF expression.
Age-related cognitive decline
Modest effect; EGb761 extract shows benefit
Dementia
Systematic reviews show inconsistent results
Intermittent claudication
Modest increase in walking distance
Antioxidant support
Well-documented free radical scavenging
| Drug | Severity | Description |
|---|---|---|
| Warfarin (Coumadin) | Severe | Ginkgo biloba may increase the anticoagulant effect of warfarin, significantly increasing the risk of bleeding including intracranial hemorrhage. |
| Ibuprofen (Advil) | Moderate | Combining ginkgo with ibuprofen may increase bleeding risk. A case of fatal intracerebral hemorrhage has been reported with this combination. |
| Clopidogrel (Plavix) | Severe | Ginkgo may enhance the antiplatelet effects of clopidogrel, increasing bleeding risk. |
| Trazodone | Moderate | A case of coma was reported in an elderly patient taking ginkgo with trazodone. The combination may enhance sedative effects. |
| Aspirin | Moderate | Ginkgo combined with aspirin may increase bleeding risk. Cases of spontaneous bleeding including hyphema (eye bleeding) have been reported. |
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