PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 8 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
n-hexane leaf extracts showed significant inhibitory activity against COX-1 (IC50 = 0.97±1.9 µg/mL) and COX-2 (IC50 = 1.13±0.2 µg/mL) in vitro, performing better than indomethacin [PMID:33122934]
Methanolic leaf extract significantly lowered serum levels of bilirubin, aspartate aminotransferase, and alanine aminotransferase, and decreased malondialdehyde (MDA) levels in albino rats [PMID:21877945]
Evidence summary
PubMed sources
- 1.PMID: 33122934 (2020) — Grewia mollis Leaf Extracts and Fractions Demonstrated Good Inhibitory Activity on Pro-Inflammatory Enzymes and with Lower Cytotoxicity in vitro. · Journal of inflammation research
- 2.PMID: 30391588 (2019) — Structure and physicochemical properties of Ghanaian grewia gum. · International journal of biological macromolecules
- 3.PMID: 26536530 (2015) — Starch-free grewia gum matrices: Compaction, swelling, erosion and drug release behaviour. · International journal of pharmaceutics
- 4.PMID: 36190603 (2022) — Seasonal food changes and feeding behaviour adaptations of savanna chimpanzees at Nguye in Ugalla, Tanzania. · Primates; journal of primatology
- 5.PMID: 28903068 (2017)