PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 1 PubMed articles · model: gemma4:31b
Summary
Trichosanthes peel contains polysaccharides that have demonstrated antiaging activity in animal models [PMID:28987375].
Background
Trichosanthes peel is a source of polysaccharides, such as TPP-1, which can be further modified through phosphorylation to create PTTP-1 [PMID:28987375].
Active compounds
Polysaccharides (TPP-1) and phosphorylated polysaccharides (PTTP-1) [PMID:28987375].
Mechanism of action
In D-galactose-induced aging mice, TPP-1 and PTTP-1 increased levels of superoxide dismutase, catalase, and glutathione peroxidase while reducing malondialdehyde [PMID:28987375].
Evidence summary
The available evidence is limited to a single in vivo animal study focusing on antiaging properties, representing a low level of clinical evidence.
PubMed sources
- 1.PMID: 28987375 (2017) — Phosphorylation and antiaging activity of polysaccharide from Trichosanthes peel. · Journal of food and drug analysis