PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 16 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Methanolic extract reduced oxidative stress induced by high D-glucose and H2O2 and stimulated NO levels in HUVECs in vitro [PMID:33228801]
Ethanolic and aqueous extracts demonstrated antibacterial activity in vitro, with root extracts showing the highest activity and promising control over P. aeruginosa [PMID:32543964, PMID:33708110]
Enriched phenolic fractions showed antitumoral effects in MCF-7 (breast) and AsPC-1 (pancreatic) cancer cell lines in vitro [PMID:34641482]
Hydrocolloid films loaded with G. tinctoria extracts showed dermal anti-inflammatory activity in mouse ear tests and wound healing properties in a rat model [PMID:31976835]
Methanol and methylene chloride extracts demonstrated antithrombin activity of 78% or higher in a chromogenic bioassay [PMID:10967467]
Evidence summary
PubMed sources
- 1.PMID: 33621871 (2021) — Alien plant introductions and greenhouse gas emissions: Insights from Gunnera tinctoria invasions. · The Science of the total environment
- 2.PMID: 33228801 (2020) — Improvement of endothelial function by Gunnera tinctoria extract with antioxidant properties. · Biological research
- 3.PMID: 32543964 (2021) — Antibacterial potential assessment of Nalca (Gunnera tinctoria Mol.) ethanolic extracts. · Natural product research
- 4.PMID: 33708110 (2020) — Chilean Rhubarb, Gunnera tinctoria (Molina) Mirb. (Gunneraceae): UHPLC-ESI-Orbitrap-MS Profiling of Aqueous Extract and its Anti-Helicobacter pylori Activity. · Frontiers in pharmacology
- 5.PMID: 35567226 (2022)