PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Isolated compounds from G. conopsea provided protection against oxygen-glucose deprivation/reoxygenation (OGD/R) injury in rat PC12 cells, with compound 17 demonstrating the most potent neuroprotective effect [PMID:39339384].
The plant and its constituents possess tonifying, anti-oxidative, anti-viral, immunoregulatory, antianaphylaxis, antigastric ulcer, sedative, and hypnotic activities [PMID:28217096].
Evidence summary
PubMed sources
- 1.PMID: 40843366 (2025) — Gymnadenia conopsea orchid: a systematic review. · Frontiers in pharmacology
- 2.PMID: 36706932 (2023) — Gymnadenia conopsea (L.) R. Br.: Comprehensive review of propagation and breeding, traditional uses, chemical composition, pharmacology, quality control, and processing. · Journal of ethnopharmacology
- 3.PMID: 28217096 (2017) — Gymnadenia conopsea (L.) R. Br.: A Systemic Review of the Ethnobotany, Phytochemistry, and Pharmacology of an Important Asian Folk Medicine. · Frontiers in pharmacology
- 4.PMID: 32085417 (2020) — Rapid Characterizaiton of Chemical Constituents of the Tubers of Gymnadenia conopsea by UPLC-Orbitrap-MS/MS Analysis. · Molecules (Basel, Switzerland)
- 5.PMID: 39031866