PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 9 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Mamaki prevents dementia by repairing neurons and ameliorating neuropathology in four different mouse models [PMID:37783918]
Extracts showed selective anti-viral activity against Herpes Simplex Virus-1 and 2 and Vesicular Stomatitis Virus [PMID:8786654]
Methanol and water extracts of leaves and bark achieved high selective inhibition of virus replication with very low cytotoxicity [PMID:23194626]
Extracts showed growth inhibition of Staphylococcus aureus and Streptococcus pyogenes [PMID:8786654]
Evidence summary
PubMed sources
- 1.PMID: 37631137 (2023) — A Comprehensive Insight into Māmaki (Pipturus albidus): Its Ethnomedicinal Heritage, Human Health Research, and Phytochemical Properties. · Plants (Basel, Switzerland)
- 2.PMID: 18034755 (2007) — Major phenolic acids and total antioxidant activity in Mamaki leaves, Pipturus albidus. · Journal of food science
- 3.PMID: 30708675 (2014) — First Report of Rust Caused by Pucciniastrum boehmeriae on Māmaki (Pipturus albidus) in Hawaii. · Plant disease
- 4.PMID: 41011270 (2025) — Evaluation of Proliferative Activity of Hawaiian Plants on PC-12 and Neuro-2a Cells and Their Effect on the TPH and TH Genes. · Pharmaceuticals (Basel, Switzerland)
- 5.PMID: 37783918 (2024)