PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ethanol extract of H. coronarium arrests cell cycle progression, induces apoptosis, and impairs migration and invasion in HeLa cervical cancer cells [PMID:30655700]. Coronarin D inhibits growth and induces death of glioblastoma and carcinoma cell lines in vitro [PMID:32334892].
Rhizome extracts act as natural inhibitors of $\alpha$-amylase and $\alpha$-glucosidase [PMID:30325249].
Extracts show antimicrobial activity against Staphylococcus aureus, Cutibacterium acnes, Bacillus subtilis, Micrococcus luteus, Pseudomonas aeruginosa, and Escherichia coli [PMID:38275337, PMID:42308121].
Rhizome extracts demonstrate antioxidant properties and inhibit collagenase, elastase, and hyaluronidase [PMID:38139864, PMID:42076095].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 32354114 (2020) — Uncharted Source of Medicinal Products: The Case of the Hedychium Genus. · Medicines (Basel, Switzerland)
- 2.PMID: 26559362 (2015) — Phytochemistry and pharmacology of ornamental gingers, Hedychium coronarium and Alpinia purpurata: a review. · Journal of integrative medicine
- 3.PMID: 30325249 (2020) — Hedychium coronarium Rhizomes: Promising Antidiabetic and Natural Inhibitor of α-Amylase and α-Glucosidase. · Journal of dietary supplements
- 4.PMID: 37514241 (2023) — Variation in the Chemical Composition of Endemic Specimens of Hedychium coronarium J. Koenig from the Amazon and In Silico Investigation of the ADME/Tox Properties of the Major Compounds. · Plants (Basel, Switzerland)
- 5.PMID: 32334892