PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 7 PubMed articles · model: gemma4:31b
Summary
Background
Active compounds
Mechanism of action
Clinical evidence
H. alpinum flowers enhanced glucose uptake in normal and insulin-resistant HepG2 cells via AMPK signaling [PMID:39364571]
Alpizarin, isolated from the aerial part of H. alpinum, demonstrated antiviral (antiherpetic) effects [PMID:3191986]
Alpizarin possesses anti-inflammatory properties and enhances reparative processes in the gastric mucosa [PMID:3191986]
Alpizarin demonstrated cardiostimulant and capillary-strengthening properties [PMID:3191986]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 25712296 (2015) — Presence of L-canavanine in Hedysarum alpinum seeds and its potential role in the death of Chris McCandless. · Wilderness & environmental medicine
- 2.PMID: 39364571 (2026) — Targeting insulin resistance: myricetin and isorhamnetin from Hardwickia binata, and luteolin from Hedysarum alpinum enhance glucose uptake and AMPK signaling in HepG2 cells. · Natural product research
- 3.PMID: 16132212 (2005) — Characterization of condensed tannins purified from legume forages: chromophore production, protein precipitation, and inhibitory effects on cellulose digestion. · Journal of chemical ecology
- 4.PMID: 3191986 (1988) — [Pharmacological properties of the new antiviral preparation alpizarin]. · Farmakologiia i toksikologiia