PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Aqueous extracts significantly increased glucose uptake in L6 and C3A cell lines; BAQ extract inhibited α-amylase and α-glucosidase [PMID:33968374].
H. petiolare extract demonstrated the best nitric oxide scavenging activity among four tested Helichrysum species [PMID:35448730].
Essential oils displayed activity in the 5-lipoxygenase assay, indicating anti-inflammatory activity [PMID:15507345].
Dicaffeoylquinic acid inhibited Escherichia coli at 512 μg mL-1 [PMID:35236074]; however, essential oils showed low antibacterial activity against S. aureus, E. coli, and P. aeruginosa [PMID:36235472].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 33968374 (2020) — In vitro evaluation of the anti-diabetic potential of Helichrysum petiolare Hilliard & B.L. Burtt using HepG2 (C3A) and L6 cell lines. · F1000Research
- 2.PMID: 36235472 (2022) — Chemical Study and Comparison of the Biological Activities of the Essential Oils of Helichrysum petiolare, H. cymosum, and H. odoratissimum. · Plants (Basel, Switzerland)
- 3.PMID: 35236074 (2021) — Phenylpropanoids and flavonoid from Helichrysum petiolare Hilliard & B. L. Burtt. · Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti
- 4.PMID: 15507345 (2004) — In vitro biological activity and essential oil composition of four indigenous South African Helichrysum species. · Journal of ethnopharmacology
- 5.PMID: 35011387