PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Aqueous extract of seeds increased urine volume and levels of calculus inhibitors (magnesium, citrate) while decreasing promoters (calcium, oxalate, uric acid, urea) and preventing kidney pathological changes in rats [PMID:32637686].
Seed extract and phenolic acids (p-coumaric and ferulic acid) attenuated elevated serum marker enzymes (AST, LDH, CPK-MB), cholesterol, and triglycerides, while restoring antioxidant enzymes in the hearts of isoproterenol-induced rats [PMID:27091200].
Treatment in high-fat diet-induced rats decreased serum glucose, total cholesterol, triglycerides, VLDL-c, and body weight, while increasing HDL-c [PMID:33368458].
Ferulic acid extracted from horse gram demonstrates antileukemic properties, with efficacy further enhanced by selenium-supplemented fermentation in HL-60 human leukemia cells and mouse models [PMID:42003100].
Supplementation in rats significantly increased activities of antioxidant enzymes including superoxide dismutase, catalase, and glutathione peroxidase [PMID:28987361].
Evidence summary
PubMed sources
- 1.PMID: 39656760 (2024) — Traditional uses, phytochemistry, pharmacology, and nutraceutical potential of horse gram (Macrotyloma uniflorum): A systematic review. · Journal of food science
- 2.PMID: 34591246 (2022) — In vitro exposed magnesium oxide nanoparticles enhanced the growth of legume Macrotyloma uniflorum. · Environmental science and pollution research international
- 3.PMID: 41271812 (2025) — Multi-model-based validation of multi-environment trial results in horse gram (Macrotyloma uniflorum Lam. Verdc.). · Scientific reports
- 4.PMID: 41076892 (2025) — Dual modification of horse gram protein (Macrotyloma uniflorum) via acetylation and ultrasonication: Enhancing functional and digestibility properties. · Food chemistry
- 5.PMID: 32180644