PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 27 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ethanolic extracts showed broad-spectrum antimicrobial activity against Gram-positive (S. aureus) and Gram-negative (P. aeruginosa) strains isolated from canine ear swabs [PMID:37104420].
Intraperitoneal injection of a high dose (1000 mg/kg) significantly increased paw withdrawal latency in inflamed paws of rats [PMID:14595582].
S. tectorum extract was assessed for protective effects on reproductive biomarkers in male rats exposed to aluminum [PMID:38672344].
Administration of extract in hyperlipidemic rats increased the excretion of aluminum, boron, and barium into the bile fluid [PMID:14713548].
Purified fractions were investigated for potential wound healing activity and cell proliferation using HCT 116 cells [PMID:31168900].
Evidence summary
PubMed sources
- 1.PMID: 40292572 (2025) — Influence of location and season on phenolic composition and antioxidant activity of Sempervivum tectorum. · Natural product research
- 2.PMID: 37104420 (2023) — Antimicrobial Activity of Sempervivum tectorum L. Extract on Pathogenic Bacteria Isolated from Otitis Externa of Dogs. · Veterinary sciences
- 3.PMID: 12696970 (2003) — Antioxidant activity of Sempervivum tectorum and its components. · Journal of agricultural and food chemistry
- 4.PMID: 22785376 (2012) — Characterization of phenolic compounds and antinociceptive activity of Sempervivum tectorum L. leaf juice. · Journal of pharmaceutical and biomedical analysis
- 5.PMID: 37269574 (2023)